Evaluation of Endoscopic Mucosal Band Ligation for Treatment of Portal Hypertensive Gastropathy in Cirrhotic Patients

Abstract

Background: Portal hypertensive gastropathy (PHG) is a clinical condition that can lead to chronic gastrointestinal (GIT) hemorrhage in cirrhotic patients, presented by chronic anemia. The diagnosis is based on the endoscopic features. The aim of the study was to evaluate the safety and efficacy of the use of endoscopic mucosal band ligation for treatment of portal hypertensive gastropathy in cirrhotic patients.

Patients and methods: This prospective study included 80 cirrhotic anemic patients. They divided into four equal groups: Group (A) included patients who were treated with drugs as beta-blockers. Group (B) included patients treated with argon plasma coagulation (APC). Group (C) included patients treated with endoscopic mucosal band ligation and Group (D) included patients treated with combined endoscopic mucosal band ligation and APC in subsequent sessions.

Results: There was statistical significant decrease in TIBC throughout follow up in the four studied groups. And there was statistical significant increase in Hb, and serum ferritin throughout follow up in the four studied groups.

Conclusion: after 2^nd follow-up in managing PHG, we have found that there is significant increase in Hb, serum ferritin and significant decrease in recurrent GI bleeding among all groups.